great info…i always seem to get confused with SERMS and AI’s … I always thought Clomid and Nolvadex were basically the same except with Nolva being stronger…I obviously have gotten confused with all the info. That and i tend to research things before doing a cycle but then after the cycle I have forgotten most of the stuff since im not working with it regularly.
The AI i used before was Arimidex? Would Arimidex be effective here? How long should I use the AI? Im currently on 20mg of Nolva daily…should i stop that immediately and then start the AI or what would be the best course of action?
Also what are your thoughts on HCG …I used it during the cycle but my nuts havent come back fully…should i use it again at lower dosages? Not much experience with this…your knowledge and advice would be appreciated.
Anyway, I Must say I like the way you explain things, simple and to the point. Very helpful. Thanks again Bill.
[quote]Bill Roberts wrote:
Glad to help!
Nolvadex binds to estrogen receptors. In some tissues, the receptor is unactivated by the Nolvadex (tamoxifen) and so the Nolvadex, at moments when binding the receptor, blocks estrogen from acting.
In other tissues, Nolvadex actually activates the estrogen receptor and so behaves estrogenically.
This is unfortunately the case in the skin, which is why Nolvadex increases acne.
Its action in blocking the effect of estrogen in the hypothalamus can and usually does result in increased LH production, which stimulates greater testosterone production.
Unfortunately, along with greater T product comes higher estrogen production, as there is more T available for the body to convert to estrogen.
To control estrogen levels, an aromatase inhibitor (AI; also called anti-aromatase) is needed.
While dosages should be checked with blood testing, a reasonable starting point is about 0.36 mg letrozole per day, or about 0.72 mg every other day. This is an amount corresponding to taking a total of 2.5 mg per week.[/quote]