Caber is likely necessary with anything more than say 200mg/wk of tren or deca, but everyone reacts different. I'd skip the tren first cycle. Add new compounds one at a time so you know how each affect you.
Tren would be the real risk of limp dick here but mitigated with caber. The other potential culprit would be uncontrolled E2, so take an AI starting day one before sides ever occur and adjust as necessary. Your libido can crash with high or low estrogen, but being an AI over-responder is rare and it's easier to fix low estrogen than high.
Acne is mostly genetic, but also can be minimized by controlling E2 and keeping your skin clean. Some people get it real bad and use low dose Accutane to control it.
Hair loss is also genetic and highly individual.
Take hCG from day one in the ballpark of 250iu EOD or 500iu twice a week. Varying recommendations on this. Just take it, it will make recovery easier and keep your balls from shrinking and possibly aching on cycle.
Opt for a longer, lower dose PCT rather than a shorter tapered style that's starts with a high dose. 8 weeks on 20mg of Nolvadex or 50mg clomid per day should do the trick. There is a study that shows 20mg of Nolvadex is more effective than 100m of clomid. Recovery is never a guarantee but hCG from day one, AI from day one, and extended PCT, is probably the best way to set yourself up for success.
Hope that helps.