T Nation

28 Year Old Seeking Help


#1

Age 28 years
Height 170 cms
Weight 120 pounds trouble in gaining weight. I add only small amount lean muscle mass while on training.
Waist 29 inch
Body and facial hair : hairy legs, average beard and regrow well in 1 week. Chest hair not much but visible.
Fat: lean and tonned body fat percent will be very low, abs are permanent.
Health conditions: no known health conditions.
Rx Otc drugs: used 5-6 years back for short duration.
Diet: Pure vegeterian diet . Additonally I take omega 3 capsules.
Exercise: On average 4 times a week. Each day 45 minutes session only.

I have basic information of endocrinology and not new to this forum.

Today I got my labs after a gap of almost 1 year.
Total T 717.86 ng/dl (241- 827)
Free T 22.80 pg/ml (8-50)
E2 31.8 pg/ml < 39.8
Lh 3.59 miu/l
Fsh 3.41 miu/l

Lipid profile

Cholestrol 177 mg/dl ( 130- 240)
Triglyecrides 66 mg/dl (65- 165)
Hdl 38 mg/dl (>35)
Non- hdl 139 mg/dl 130 -150
Ldl 126 mg/dl upto 130
Vldl 13 mg/dl
Cholesteol/hdl ratio 4.66
Ldl/hdl 3.32

My TSH has been in range of 2.5 to 4 in past 3 years and sometimes my feet are very cold even in summer. My doctor says these are normal levels and do not treat. I know it should be around 1.

What should be next course of action . Please give insight about my T profile.


#2

This is your 8th topic. Not checking old topics, but have we covered this ground before?

HDL might be better with more B vitamins which your diet can easily lack.

TSH=2.5-4 is a problem.
You need to be using iodized salt and/or supplementing in a multi-vit that lists iodine and selenium. Selenium is very important in this situation.

I have never seen a report of a doc asking about iodine. He will not treat, but you can.

Eval overall thyroid function via last paragraph in this post.

E2 is too high, getting closer to E2=22pg/ml should improve LH/FSH, lower SHBG, lowering SHBG+T and increasing FT. You can try 0.5mg anastrozole per week in divided doses. Your doc probably is uninterested.

A high potency B-complex multi-vit with trace elements including 150-180mcg iodine and 150-200mcg selenium would address multiple issues. Most men do not need added iron and should avoid vitamins that list iron. Can you post your CBC?


#3

Today I got anastrozole produced by local pharma company in my country. Arimidex is very costly . I can not ask for bloodwork again , lab do not do in short period of time. So would you advise me to still go for anastrozole without any blood work .
what time of day it is most effective?
what are the chances it would address my issues.
If I am hypothyroid why I am not overweight and find it difficult to gain weight even after eating more than enough calories??
@KSman


#4

Some guys [me] simply cannot gain weight - and my wife gets mad about me eating anything I want.

Arimidex is a brand name for anastrozole, you have the right drug.
Try 1/4mg twice a week and observe how you may feel different after a week. If you feel crashed, stop for 5 days and restart with 1/8mg twice a week.

After a while with lower E2, SHBG will decrease and FT should increase and perhaps TT will too.

Please consider my comments re B vitamins, iodine and selenium. You might find all in a multi-vit. Some aspects of the effects deficiencies of these might be contributing to your lower T levels.


#5

I am starting with 1/8 mg twice a week and see how I feel and will post my experience accordingly.
Today I am taking dosage after dinner but have doubt at what time of day it is most effective??? In night time T production takes place so with this idea in mind I am taking after dinner.
@KSman


#6

From work with females it was determined that anastrozole is very bio-available and time of day or meals did not seem to be a factor *, suggest empty stomach and a bed time routine may suit you.

  • Any effects of decreased absorption with food would be hard to detect because of the long half-life.

#7

This time I have already taken after dinner next time will take empty stomach.Thanks so much for quick response.
You rocks ksman


#10

How are those T levels a problem?


#11

You could get E2 tested and then based on that calculate a corrected AI dose. If you have E2=30 and target is 22, new dose = old dose X 30/22


#14

Please consider my comments re B vitamins, iodine and selenium. You might find all in a multi-vit. Some aspects of the effects deficiencies of these might be contributing to your lower T levels.

Your thyroid function is very critical to energy/vitality, libido and mood.
Why are you ignoring this issue.

Your diet may be part of this problem.


#15

I will include a good multivitamin and then see how things workout. Anastrozole certainly has lifted my mood and I am more energetic and focused on work in office as well as home. Now trying to increase protein intake since I am vegetarian it is hard part for me and I do not want to have whey protein powder also since it is not inspected properly and can be adulterated with steroids. So eggs plus good multivitamin with iodine and selenium.


#16

That is funny when most here are injecting testosterone.


#18

Your own E2 is certainly hugely more of a factor than any hormones in milk could be. Any BST [growth hormone] in milk would be denatured in the drying and processing.


#21


How is my lipid profile and I have decided to take control of thyroid since all my doctors are ignoring it.
What dosage should I start??
@KSman