Awhile ago i posted some results of bloodwork done in my early 20;s. My levels was scraping the bottom of the range and of course got a message on the answering machine from a fat receptionist eating cheetos saying?sir your with in the normal range, have a good day?. I didn?t expect anybody to give a dam then or now. Thats why i created this thread; in the hopes of clarifying the knowledge I can gather to treat ourselves and hopefully its useful to all who stumble down this thread.
My internet sucks donkey dick but will try to copy and paste excerpts here that seem relevant. Helps to keep alot of these different hormone variables and how they interact with each other straight in your head. Thanks Mac, curious why started to crash at 6mo mark.
This link shows why decided to low dose it
http://tnation.T-Nation.com/free_online_forum/sports_training_performance_bodybuilding_trt/secondary_hypogondadism_estradiol_out_of_control
MOds have said the link cant be put here but if you search “Clomid 12.5mg m,w,f” the first result should have more info on this dosing as well as the added Arimidex.
Excerpts relating to this.
dhickey “Blood work will tell the story. My E2 rose with T, which would definitely counteract any benefit of increased T. If T and E rise, you can try knocking E down and see how you feel. Worse case it will provide some diagnostic info. If LH/FSH are high but T is low, you know you are primary and need to look at replacement. If LH/FSH are still low, you can probably assume you are secondary.”
KSman: "Do not ever do a dead stop on a SERM, always taper off!
When on SERM, test LH, FSH, T and FT.
- if LH/FSH still low, top end of HPTA is broken, start TRT
- if LH/FSH good and T low, testes not working, start TRT
LH/FSH should increase quite fast. However, the testes take time as physical changes need to occur, so do not rush T testing. If DHEA-S is low, DHEA–>T may be limited.
If SERM dose is too high, LH will be high. There are two risks. One is desensitization of the LH receptors. Second, T–>E2 inside the testes can be very high and competitive AI’s cannot control that. Suggest 1/2 dose SERM dosing."
http://tnation.T-Nation.com/free_online_forum/sports_training_performance_bodybuilding_trt/estradiol_why_you_should_care The first post about E2 worth reading. Have read many time that E2 cant be accurately tested while on clomid.
QUESTiONs
1)Whens the correct time to add Arimidix to the clomid use? I understand people respond with different sensitivity to AI and SERMS. I believe generally, if your on the young side then youll be more sensitive and need less of a dose? I was thinking of starting to add Arimidix after 2 weeks of clomid use. Not sure to go with .25mg EOD or .25mg every 3rd day .
2)Has any protocol(or length of time) been shown most likely to result in elevated Test levels after tapering off everything?
3)Clomid use for multiple months results in desensitizing the pituitary to GnRH?
Im guessing this is a problem mostly associated with “SERM dose is too high, LH will be high. There are two risks. One is desensitization of the LH receptors.” Another reason to low dose.
“One other side effect of Clomid to keep in mind is that over the long term, and especially at higher dosages, the pituitary gland is desensitized to GnRH. Therefore, a short run of low dose Clomid,if successful in increasing testosterone production, is best looked at as a way to kick start the hypothalamus and pituitary gland into successfully working at full potential”
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How long to wait before getting bloodwork to test the results, im thinking around 2 months?
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Best hour to take Arimidix? Probably will take clomid around 10am… Take the AI same day as clomid or not?