24 Y/O Pre-TRT Levels w/ ED & Depression. Thinking of Going Off

Low T and high LH indicates that your testes stopped working. Nothing can be done about that unless there are surgically correctable vascular abnormalities. Did doc examine your testes?

Current TRT:
250mg T cyp one injection per week
1mg anastrozole at time of injections

For most guys, ~1mg anastrozole is needed for each 100mg T ester. So you can expect to now have high E2 and that would explain your current issues.

250mg is way to high for TRT, but you have done it. You now have high T–>DHT driving hair loss.

Suggest:

  • Self inject 75mg twice a week, subq with #29 1/2" 0.5ml insulin syringe, over upper leg.
  • .75mg anastrozole at time of injections or 0.5mg three times per week
  • 250iu hCG subq EOD to recover testes and try to recover fertility

How much have testes shrunk?
Do they have a dull 24x7 ache?

Labs: - after 4 weeks on above
TT
FT
E2 - needs to be able to resolve low E2 levels, depends on lab company
CBC
hematocrit - might be high now
FSH - only one time to screen for testicular caner, FSH should ~=zero
AST/ALT

Do not ignore the last paragraph.

Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.