KSman I have an update on my situation after attempting a HPTA restart and supplementing with iodine and selenium, I have had 4 sets of blood work to track my progress, it is progressing in the right direction however will need to do one more blood test 4 weeks after the restart to really find out if it has worked. Apologies in advance for the long post. Could you please give me some advice on my results.
First test - 12 May 2016
SHGB 21.37 nmol/L
TOTAL TEST - 6.82 nmol/L
beta 17 Ostradiol - 18.35 pmnol(Low)
ALBUMIN - 51.7 g/L
FREE TEST - 0.147 nmol/L
FSH - 6.27 IU/L
Cortisol 692.82 nmol/l
TSH - 1.74 mU/L
Free T4 - 16.65 pmol/L
I have added the increase or deacrese In values so you can see progress from the previous set of results.
Second test - June 17 2016
SHBG level - 33 nmol/L (+11.63nmol/L)
Total test - 17.2 nmol/L (+10.38 /L)
Albumin - 48 g/L
Free test - 0.341 nmol/L (+0.167 nmol/L)
FSH 6.4 U/L (+ 0.13 U/L)
LH - 4.4 U/L
Cortisol - (AM) 349 nmol/L (- 343 nmol/L)
TSH - 1.66 mu/L (- 0.8mu/L)
Free T4 13.89 pmol/L (- 2.76 pmol/L)
Prolactin - 206 mU/L
HPTA RESTART Protocol
(Week 1-2) 20mg Tamoxifen (ED) 0.5 Adex per week
(Week 3) 10mg Tamofixen (ED) 0.5 Adex per week
(Week 4) 5mg Tamofixen (ED) 0.75 Adex per week
(Week 5) - 6 Taper off Adex at 0.25 for 2 weeks to prevent rebound.
Supplements through out HPTA restart attempt. And carrying on from now on.
Ashwashgha - 1800 mg ED
Omega - 3 x 3 ED
Selenium 200ug x 1 ED
Iodine - 0.45 mg ED (3 x 150 ug)
Vitamin D3 10 ug x 3 ED
Berroca multivitamin 1x ED
Milk thistle ED
Test 3 - Week 3 of HPTA restart.
12 August 2016
Total test - 29.54 Nmol/L. (+ 12.34 Nmol/L )
17beta estradiol - 49.4 pmnol( + 31 pmnol )
Test 4 - 23 August 2016
SHGB level - 40.69 Nmol/L ( + 7.69 Nmol )
Total test - 28.72 Nmol/L. ( - 0.82 Nmol/L )
Beta 17 ostradil - 18.83 Pmnol (- 30.57 )
Albumin - 47.2 g/l. ( - 0.8 g/l )
Free test - 0.558 nmol/L. ( + 0.217 )
FSH - 10.01 IU/L. ( + 4.61 IU/L )
TSH - 3.02 mIU/L. ( + 1.36) !!!!!
Free T4 - 15.13 pmnol/L. ( + 1.24 ) pmnol/L
I have a few questions regarding my progress.
First of all does the increase in FSH induced by Tamoxifen suggest that my condition is not caused by primary hypogonadism and could be secondary, I'm thinking induced by stress and thyroid issues.
This brings me on to my next question, since supplementing with iodine and selenium my TSH has increased from 1.74 to 3.02 so has nearly doubled yet T4 output has stayed relatively the same, what does this suggest? Could it simply be the thyroid awakening after a long time of iodine deficiency, I think it's important to add as a child I was lactose intolerant something I have grown out of but still do not drink milk regularly and drank very little as a child.
Libido wise I improved during the HPTA restart gaining morning wood for the first time in years, desire came back strong as well however this came and went through out. Since stopping however things have slowly returned to how they where before I believe this is due to my Estrogen crashing again possibly due to over dosing the Adex in my final week.
Any opinions or advice anyone could give me would be greatly aprecieated given my age I'm am looking to explore all avenues before committing to TRT. will update with final blood work in a few weeks.e