21, On Thyroid Meds. Low FT, High LH, High SHBG. Read All Stickies

Your numbers in the first post aren’t entirely dissimilar to mine, except my total testosterone is 200 to 300 points lower.

According to the calculator at ISSAM your free testosterone is 12.6 pg/mL, which is closer to your historic levels. I’ve got a feeling that direct measurements can be problematic.

There’s evidence that low (calculated) free testosterone can be used to diagnose hypogonadism, but the cut off researchers used is 6.5 pg/mL, which is about half your level.

Where I think might be worth digging into are your LH and FSH levels. Compensated or subclinical hypogonadism is when these are high, and your testosterone levels are normal. (See the ISSM and the Nebido site for more.)

In my case (and possibly yours), whilst testosterone levels look fine, the high LH and FSH levels indicate that my (and your) body needs more, but cannot produce it.