Hi, I have been on TRT for about 3 years. I’m 38 years old. It has been an extraordinary roller coaster. I have taken a ton of advice from these forums but I’m still not in good shape. Here is the quick rundown on labs.
TT - 210 (280 - 900)
E2 - 10
FT - 5 (6 - 25)
On 100mg Test CYP IM E7D - Peak
TT - 1520 (280 - 900)
FT - 36 (6 - 25)
E2 - 30
On 100mg Test CYP IM E7D - Trough
TT - 480
FT - 12
E2 - 14
I was on this protocol for about a year. In general better mood, better quality of life, libido was hit or miss, ED occasionally. BUT the last 3 months on this protocol I was really noticing the drop towards day 5, 6 and 7 in energy. Very fatigued. Libido totally dried out. It was affecting my day to do.
Some other things of note -
SHBG - 24 - Very consistent. Had this tested multiple times
DHT - At peak on 100mg - DHT was towards the very high end
DHT - At trough - DHT was towards the middle
DHT - At Peak and Trough at 70mg E3.5D was in the middle
DHEA - In the middle
Thyroid - checked multiple times. Results were average. No issue.
Vitamin D - Lower end
Magnesium lower end
Had labs checking almost everything you can check. Everything else was normal.
Switched to 70mg Test CYP IM E3.5D
Day after shot
TT - 820 (280 - 900)
FT - 24 (6 - 25)
E2 - 22
Day of next shot (trough)
TT - 630 (280 - 900)
FT - 20 (6 - 25)
E2 - 20
Here’s the issue. I’ve developed some crazy symptoms…
Irregular Heartbeat/Heart Paplitations
Occasionally I’ll get join pain
Just feel absolutely terrible
If I up my dose to 100mg, the symptoms go away but DHT goes too high. TT is too high, FT is high. I tried this E4D and E5D to not hit a trough but still spiked too much. I get extreme acne and hair loss as well. My numbers aren’t bad at the lower dose but the symptoms are incredible hard to manage. I thought it might be blood thickening but my hemotocrit has always been low to mid 40s.
Also, I would sit on a protocol for at least 6 weeks. So I always give it time to normalize. And notice how my e2 does not spike. I have never needed an AI.
I’m thinking of switching to androgel. Or frankly getting off of T totally. These symptoms have become too hard to manage.
Has anyone been through anything like this at all? Any suggestions on what to do? If I drop TRT the symptoms go away. I’ve taken a couple week vacation from it but then all the horrible symptoms of low T kick in.