1st TRT Follow-Up Lab Results

I have been taking 200mg test cyp a week for 8 weeks. Taking 86 mg every 3 days IM and i got the blood test done 1.5 days after a pin (so in between the pins).

I have not been taking any AI because i wanted to just see if i could get away without needing multiple things. I havent had any high estrogen symptoms but seems my e2 is high. I have anastrazole 0.25 mg. I was thinking taking it twice a week a day after each pin?

Also my total Test is 1347 and free is 271. So i also was going to lower the dose some to stay in the more normal range. I know the labs were taken probably a little after the peak action but i would think with every 3 days it would be a little more stable and not totally off from what it is on average.

Also rbc, hct and hgb are high so i thought about donating a unit of blood.

So basically what do you all think about these labs and recommendations about the lower dosage and adding in anastrazole?

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Lower dose sure, but this isn’t your lowest point during the week. Kinda in the middle. So lower the dose first and see how you feel. If you still have some high e2 symptoms after that then add in the AI

No surprise here, this should have been expected because 200 mg weekly is at the upper end for TRT dosages.

I would drop the weekly dosage down to 120-140 mg.

Ya i wanted to start high and work down. I was thinking like trying 140 and then seeing what estradiol is. I would like to stay away from an AI. Like i said though if i wouldnt have checked the e2 i wouldnt have known it was high because not having any high e2 symptoms.

A couple of things:

Those levels are expected, not so much due to the dose, but the timing of the blood draw. They would likely drop around 15% if at the trough.

How at you feeling? You have no E2 symptoms, and many do not with levels like yours and even higher, only benefit. Absent symptoms, I would not worry about the E2. You do not need to donate blood, unless your BP is up or you are feeling discomfort. You can, but it is not necessary. But you are only two months in, and you are at 52%. (where was it initially?) I would expect it to go higher with more time, so perhaps it may be a good idea to get a handle on it. Make sure you are well hydrated. I’ve had many guys with increased hct due to that. Fasting labs, first thing in the am, they do not eat, but drink no water as well.

I feel really good. My BP is usually normal. Highest i have see is 130s systolic. My baseline rbc was 5.14, hgb 15.5 and hct 45.9.

As far as testing, would you recommend going on the day i pin right before i pin?

I also made sure i drank adequately before i went to bed and when i got up as to not be dehydrated and inaccurately elevate my h/h.


Nice, not sure I’d change anything then.

What you’re doing is not TRT.

You can actually lower the dose and use no AI.

Thats why i got my labs checked. I dont want to be supratherapeutic aka above normal range. I want the test levels to be in a normal range but a high normal not 400. At 400s total and 60 free i felt like shit. And now feel great but would like to adjust dose enough to be in normal range but still feel great. And like i said i do not want to use AI either unless no choice.

I think i am going to try 70 mg every 3 days and see from there what test and e2 looks like. And adjust again if needed. Would like to find a dose where free and total are in normal range and the estradiol is not quite as high and where i still feel good aka no low T symptoms.

Why not just try 100 mg once per week?

I rather not have a big peak and then drop by end of week. If i was to do 100 i would still break it up to every 3 days. Like 43mg every 3. I just know from going on vacation for 8 days i took a weeks worth and i felt super good the day or 2 after and crap by day 8. But who knows maybe if still too high and for convenience i might go to that later. I even debated daily sub q shots. I feel i do better with more frequent shots and less high and low aka stable levels.

What does your doctor say?