100mg 2x/Week vs 200mg Once/Week?

Is there a difference/benefit to injecting 100mg 2x a week as opposed to 200mg 1x a week?

If you plot the doses into something like steroid calc, you’ll see that splitting the dose avoids the higher spikes and deeper troughs of taking it once per week.

Proponents of splitting the dose will say that consistent hormone levels are better. Those who take it all at once will argue that they don’t notice any difference.

My suggestion would be to try both protocols for a few weeks or month, and see what you prefer. I’ve got high SHBG, and actually feel better off taking a bigger dose less regularly. Your mileage may vary.